Does the skin breakout first then clear up ?

Every effective acne treatment can cause in the beginning a few more pimples. This is commonly seen with Accutane but can also happen in people that use antibiotic tablets, such as minocycline or topical creams such as benzoyl peroxide or adapalene (Epiduo and Differin). The cause for that is that the remains of the dead bacteria trigger a temporary, stronger inflammatory reaction that causes some more new pimples. If this happens, one should reduce the new cream application for every other day for 7-10 days and switch back to every day when till the skin calms down. With the MDacne products the effect is rare and if it happens it will subside quickly with no need for any special treatment.

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