Products / Retinol 0.25% Treatment Cream

Retinol 0.25% Treatment Cream

Gently clears acne, smooths skin, softens fine lines, best for beginners

Benefits

✓ High-strength 0.25% Retinol concentration
✓ Improves the skin's texture for a more youthful-looking skin
✓ Reduces skin blemishes
✓ Targets fine wrinkles and uneven skin tone
✓ Formulated for sensitive, acne-prone skin
✓ Vegan and cruelty-free
✓ Paraben, sulfate, and silicone-free
✓ Dermatologist designed, tested, and approved

Overview

This unique Retinol treatment cream combines the magic of high-strength 0.25% Retinol and 2.0% Niacinamide. Pure Retinol works to unclog pores and prevent acne blemishes and fine wrinkles without over-drying the skin. Niacinamide (vitamin B3), a powerful anti-inflammatory ingredient, hydrates the skin, improves the skin's texture, and helps fade post-acne dark spots.

Size: 0.5 oz | 15 ml

Key Ingredients

Pure Retinol 0.25%
A powerful Retinoid that is converted in the skin to active Retinoic acid. It increases the skin's cell turnover, unclogs pores, and helps reduce the appearance of blemishes, fine lines, and wrinkles.

Niacinamide 2.0%
A form of vitamin B3. It enhances the skin's protective barrier and helps reduce the appearance of blemishes, large pores, and hyperpigmentation.

Treatment Boosters

🌱 Tea tree oil
Potent antimicrobial and antifungal with proven medical-grade efficacy for acne.

🌿 Aloe Vera leaf extract
A powerful antioxidant that hydrates and reduces redness and irritation.

🌼 Chamomile Extract
An effective antioxidant, anti-bacterial and anti-fungal with potent skin-soothing properties.

🌸 Calendula Officinalis Extract
Highly effective anti-inflammatory and antibacterial compound used by dermatologists to soothe irritated skin.

🌻 Sunflower extract
A powerful ingredient that helps neutralize free radicals and exhibits strong anti-glycation properties.

🎋 Licorice extract
A potent antioxidant that prevents and helps fade brown spots.

How to Use

Apply your retinol cream at night on clean, dry skin. In the beginning, apply it twice per week, and gradually increase the application frequency. Apply a pea-sized amount to your finger and touch the four areas of your face: forehead, chin, and the two cheeks, avoiding contact with eyes, eyelids, and lips. Always apply sunscreen when outdoors.

Retinol products are not recommended for use by pregnant or nursing mothers.

Instructions for Women

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Instructions for Men

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Full Ingredient List

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Aqua (Deionized Water), Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Isopropyl Myristate, Glyceryl Stearate, Niacinamide, Stearic Acid, Helianthus annuus (Sunflower) Oil, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Retinol (Vitamin A), Allantoin, Melaleuca Alternifolia (Tea Tree) Oil, Chamomilla Recutita (Chamomile) Extract, Glycyrrhiza Glabra (Licorice) Extract, Thymus Vulgaris (Thyme) Extract, Calendula Officinalis Extract, Polysorbate 20, Phenoxyethanol, Ethyhexyl glycerin.

 

 

 

 

 

 

 

Your questions, answered

What is MDacne Retinol 0.25% Treatment Cream and how does it work?

MDacne Retinol 0.25% Treatment Cream is a cosmetic night cream with 0.25% pure retinol and 2% niacinamide. Retinol converts to retinoic acid in the skin and speeds cell turnover, which helps keep pores clear and smooths texture. Niacinamide calms redness and helps fade dark spots.

Is MDacne Retinol 0.25% Treatment Cream better than other retinol products?

MDacne Retinol 0.25% Treatment Cream uses pure retinol, the form your skin converts directly to retinoic acid, paired with 2% niacinamide to offset dryness. Tea tree oil, aloe vera, chamomile and calendula soothe the skin, and the formula is vegan and free of parabens, sulfates and silicones.

MDacne Retinol 0.25% or 0.5% — which strength should you start with?

MDacne Retinol 0.25% Treatment Cream is best for anyone new to retinol or with sensitive skin, since it is the beginner strength. Move to MDacne Retinol 0.5% Treatment Cream, which is twice as potent and paired with 4% niacinamide, once you tolerate nightly use comfortably.

How long does MDacne Retinol 0.25% Treatment Cream take to show results?

MDacne Retinol 0.25% Treatment Cream usually improves texture and tone by week six to eight. Fewer clogged pores and smoother skin build over three months, since you start at twice weekly. Retinol results are cumulative, so consistency matters more than frequency.

How do you use MDacne Retinol 0.25% Treatment Cream at night?

MDacne Retinol 0.25% Treatment Cream goes on at night to clean, dry skin, twice a week at first, then more often as your skin tolerates it. Use a pea-sized amount on forehead, chin and both cheeks, avoiding eyes and lips. Always wear sunscreen outdoors.

Does MDacne Retinol 0.25% Treatment Cream cause purging, and how long?

MDacne Retinol 0.25% Treatment Cream can cause more breakouts in the first two to six weeks, as retinol pushes existing clogs to the surface. Keep to twice weekly, moisturize, and let it settle rather than stopping. Message our team if breakouts worsen past six weeks.

Who should not use MDacne Retinol 0.25% Treatment Cream?

MDacne Retinol 0.25% Treatment Cream is not recommended if you are pregnant or nursing. Mild dryness, redness or flaking is common early on, so reduce frequency and use a moisturizer. Retinol increases sun sensitivity, which is why daily sunscreen is not optional with this cream.

4.5

Based on 48 Reviews
CL Verified Customer
Disappointing Customer Experience
I have been using MDacne for 1 year and 5 months. Unfortunately, I have had two disappointing experiences with this company, which I want to share with you, so you can understand what you might be getting into. My subscription was shipped on October 31, 2024. This time, the company separated the retinol treatment from the rest of the subscription, so I received two tracking numbers. A week later, I received the main subscription. When I tracked the second shipment, UPS displayed the message: "UPS doesn’t have possession of the package yet. Estimated delivery date will be available as soon as we get the package." Another week passed, and the status remained the same, so I contacted customer support. A representative, "L," responded: "I've checked the tracking information for the rest of your order and see that your package was delivered on November 6! Have you had a chance to check for it yet? It may be hiding in the mailbox." Clearly, she hadn't read my message carefully and used her templates to respond to my inquiries. I had explicitly stated that there were two packages—one of which I had already received—and I was inquiring about the one that hadn’t arrived. Another representative, "M," then stepped in, providing standard explanations and saying: "That being said, not to worry, if we still don't see an update by November 21, 2024, we'd be happy to process a replacement or issue a refund from there." She also sent me an article titled "Lost in Transit." Following her advice, I waited another week until yesterday, only to find that UPS still hadn’t received the package. I sent M a follow-up message requesting the promised refund and asking to cancel my account. Deep down, I suspected I wouldn’t receive the refund given how they had been handling my case. As expected, M responded: "As carriers have advised that, although there may not be any recent tracking updates, the packages are still in transit and should be on their way to you. Unfortunately, at this time, we are unable to consider the package as 'lost in transit.'” She added that there was no guarantee on the delivery date or time and shared another article for me to read. I wasn’t surprised by their refusal to refund my money, given their unprofessionalism. However, they never should have promised a refund in the first place. When UPS clearly shows that the package never arrived at their facility, why does this company insist that it’s "in transit"? What, then, is their definition of "Lost in Transit"? Is this a tactic to take customers' money without fulfilling orders? I’ll leave that question for you to consider. Also, it is just unprofessional to use templates to respond to customer's inquiry. If you want to market yourself as a "caring", "customer-oriented" business, you need to make sure that you LISTEN to your customers and INDIVIDUALIZE the response. 2. When I first started the subscription, I was advised to take the daily supplement, DIM. When the supplement arrived, I noticed that the expiry date had already passed. I immediately contacted customer support, and they claimed it was the manufacturer's fault—the expiry date was misprinted for that batch. Trusting their explanation, I assumed the expiry date would be correct in the next subscription two months later. However, when the next subscription arrived, the company had used a sticker with an extended expiry date to cover the "misprinted" expiry date. The sticker was poorly applied and fell off the bottle when I took the bottle out of the package. After that, I stopped the supplement. I am not sure expired supplement would do any harm to my body, but my trust to this company decreased significantly. I am not expecting anything from this company anymore. The money I lost will be for buying the experience. There are more than enough skincare products out there in the market. I will prefer to shop with peace of mind to always feeling nervous about my shipments and the expiry date of the products.
prasanthi Reddy Verified Customer
Effective and soothing
I've only been using these products for a few days, but I can already see a difference! The cleanser is amazing and makes my face feel so fresh! The moisturizer is super moisturizing and soaks nicely into my skin, my new favorite! This will be my go-to cleanser and moisturizer from now on. The Retinol is also really nice.my pimples are already fading! I'm so thrilled! Give MDacne products a try, you won't regret it!!
Martina Verified Customer
MDacne Has Literally Been
MDacne Has Literally Been “A LIFE SAVER” To Me….. Apart From Getting Your First Order Completely Free As A Trial, Just Need To Pay For P&P “Package & Postage” Which Is Only £9 GBP Your Subscription Is Personalised Especially For You & Your Skin Type As Well As Various Different Skin Problems Which Work’s💯 Don’t Be Put Off When It Starts Bringing Out All Of Your Pimples To The Surface Of Your Face/Body Ecc, This Is Called “PURGING” & It Will Completely Clear-up After “6-Weeks” Of Using The Facewash, Skin Treatment & Skin Cream (TWICE A DAY) Then Their’s Load’s Of Other Products I Can Order Too Like The Dark Spot Remover, Pore Nose Strips, Retinol & Many More Creams Which Are All Personalised Formulas Especially For Me, My Skin Type & My Skin Problems” +Supplements & This Is Not Only “TREATMENT” It Is Also A “PREVENTION” Formula Also.. I Have An Online Dermatologist At My Disposal Who Reply To Me Without Fail Within 2-Hour’s No Matter The Day Or Time. I Get Daily Tip’s On What My Skin Improvement Should Be At Each Point Of My Skin Recovery ❤️‍🩹 & I Also Get To Log My Progress So I Can See My Skin Recovery On A Chart 📈 As Well As Being Able To Interact With The MDacne Community & Give Each Other Information ℹ️ + Tip’s On Better Skin Health!! All This For “ONLY £29 A MONTH” A Bargain Is An UNDERSTATEMENT!! Thank You MDacne xx
Abby Oye Verified Customer
If you want clear skin this is your product
If you want clear skin this is your product. I experienced some dryness and itching for the first few weeks of using it but my daughter experienced none of that so I think it depends on your skin. This product is excellent and great, their customer service deserves A+.the products cleanse my over 20 years ance now am on their retinol to target my ageing skin due to my age and pass stress, Theirs medical advisor team make life so easy.
Princess Verified Customer
The products are not even worth one…
The products are not even worth one star. The moisturizer caused more acne on my face, doesn’t work at all. The retinol doesn’t work, the dark spot remover is not effective at all plus it cost so much. Please, please, DO NOT PURCHASE!!