Products / Retinol 0.25% Treatment Cream
Retinol 0.25% Treatment Cream
Retinol 0.25% Treatment Cream
Retinol 0.25% Treatment Cream
Retinol 0.25% Treatment Cream
Retinol 0.25% Treatment Cream
Retinol 0.25% Treatment Cream

Retinol 0.25% Treatment Cream

48 Reviews

Gently clears acne, smooths skin, softens fine lines, best for beginners

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Benefits

✓ High-strength 0.25% Retinol concentration
✓ Improves the skin's texture for a more youthful-looking skin
✓ Reduces skin blemishes
✓ Targets fine wrinkles and uneven skin tone
✓ Formulated for sensitive, acne-prone skin
✓ Vegan and cruelty-free
✓ Paraben, sulfate, and silicone-free
✓ Dermatologist designed, tested, and approved

Overview

This unique Retinol treatment cream combines the magic of high-strength 0.25% Retinol and 2.0% Niacinamide. Pure Retinol works to unclog pores and prevent acne blemishes and fine wrinkles without over-drying the skin. Niacinamide (vitamin B3), a powerful anti-inflammatory ingredient, hydrates the skin, improves the skin's texture, and helps fade post-acne dark spots.

Size: 0.5 oz | 15 ml

Key Ingredients

Pure Retinol 0.25%
A powerful Retinoid that is converted in the skin to active Retinoic acid. It increases the skin's cell turnover, unclogs pores, and helps reduce the appearance of blemishes, fine lines, and wrinkles.

Niacinamide 2.0%
A form of vitamin B3. It enhances the skin's protective barrier and helps reduce the appearance of blemishes, large pores, and hyperpigmentation.

Treatment Boosters

🌱 Tea tree oil
Potent antimicrobial and antifungal with proven medical-grade efficacy for acne.

🌿 Aloe Vera leaf extract
A powerful antioxidant that hydrates and reduces redness and irritation.

🌼 Chamomile Extract
An effective antioxidant, anti-bacterial and anti-fungal with potent skin-soothing properties.

🌸 Calendula Officinalis Extract
Highly effective anti-inflammatory and antibacterial compound used by dermatologists to soothe irritated skin.

🌻 Sunflower extract
A powerful ingredient that helps neutralize free radicals and exhibits strong anti-glycation properties.

🎋 Licorice extract
A potent antioxidant that prevents and helps fade brown spots.

How to Use

Apply your retinol cream at night on clean, dry skin. In the beginning, apply it twice per week, and gradually increase the application frequency. Apply a pea-sized amount to your finger and touch the four areas of your face: forehead, chin, and the two cheeks, avoiding contact with eyes, eyelids, and lips. Always apply sunscreen when outdoors.

Retinol products are not recommended for use by pregnant or nursing mothers.

Instructions for Women

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Instructions for Men

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Full Ingredient List

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Aqua (Deionized Water), Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Isopropyl Myristate, Glyceryl Stearate, Niacinamide, Stearic Acid, Helianthus annuus (Sunflower) Oil, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Retinol (Vitamin A), Allantoin, Melaleuca Alternifolia (Tea Tree) Oil, Chamomilla Recutita (Chamomile) Extract, Glycyrrhiza Glabra (Licorice) Extract, Thymus Vulgaris (Thyme) Extract, Calendula Officinalis Extract, Polysorbate 20, Phenoxyethanol, Ethyhexyl glycerin.

 

 

 

 

 

 

 

Your questions, answered

What is MDacne Retinol 0.25% Treatment Cream and how does it work?

MDacne Retinol 0.25% Treatment Cream is a cosmetic night cream with 0.25% pure retinol and 2% niacinamide. Retinol converts to retinoic acid in the skin and speeds cell turnover, which helps keep pores clear and smooths texture. Niacinamide calms redness and helps fade dark spots.

Is MDacne Retinol 0.25% Treatment Cream better than other retinol products?

MDacne Retinol 0.25% Treatment Cream uses pure retinol, the form your skin converts directly to retinoic acid, paired with 2% niacinamide to offset dryness. Tea tree oil, aloe vera, chamomile and calendula soothe the skin, and the formula is vegan and free of parabens, sulfates and silicones.

MDacne Retinol 0.25% or 0.5% — which strength should you start with?

MDacne Retinol 0.25% Treatment Cream is best for anyone new to retinol or with sensitive skin, since it is the beginner strength. Move to MDacne Retinol 0.5% Treatment Cream, which is twice as potent and paired with 4% niacinamide, once you tolerate nightly use comfortably.

How long does MDacne Retinol 0.25% Treatment Cream take to show results?

MDacne Retinol 0.25% Treatment Cream usually improves texture and tone by week six to eight. Fewer clogged pores and smoother skin build over three months, since you start at twice weekly. Retinol results are cumulative, so consistency matters more than frequency.

How do you use MDacne Retinol 0.25% Treatment Cream at night?

MDacne Retinol 0.25% Treatment Cream goes on at night to clean, dry skin, twice a week at first, then more often as your skin tolerates it. Use a pea-sized amount on forehead, chin and both cheeks, avoiding eyes and lips. Always wear sunscreen outdoors.

Does MDacne Retinol 0.25% Treatment Cream cause purging, and how long?

MDacne Retinol 0.25% Treatment Cream can cause more breakouts in the first two to six weeks, as retinol pushes existing clogs to the surface. Keep to twice weekly, moisturize, and let it settle rather than stopping. Message our team if breakouts worsen past six weeks.

Who should not use MDacne Retinol 0.25% Treatment Cream?

MDacne Retinol 0.25% Treatment Cream is not recommended if you are pregnant or nursing. Mild dryness, redness or flaking is common early on, so reduce frequency and use a moisturizer. Retinol increases sun sensitivity, which is why daily sunscreen is not optional with this cream.

4.5

Based on 48 Reviews
Adam Taylor Verified Customer
AVOID
I wrote this review and MDacne got it removed, clearly trying to hide their bad service. Awful customer service, lock you into a subscription and you can’t cancel all but 10 seconds after as apparently the order has been shipped when it hasn’t. Fraudulent practise. Somehow held my updated card details even though I hadn’t been a member for over 2 years. Avoid. Moisturiser is drying and it’s not a custom set as all the sets are the same except you may get hydrating or retinol. Cera Ve so the exact same for much cheaper and no subscription.
Aiden Mcdonald Verified Customer
Overall experience so far.
Its almost been a month and in already seeing some results the benzoyl peroxide is leave on overnight which I greatly appreciate. Havent been using the moisturizer since I use a seperate face wash for night time which has everything thats in it already and I want the dryness. The face wash is good for sensitive skin even with the saliclyc acid in it I havent noticed any cons so far. Might add a retinol product for my moisturizer. Good experience so far.
Kristina K Verified Customer
I have been using MDacne products for a 2 years and won’t stop anytime soon!!
I have been using MDacne products for a couple of years now and I’m super impressed with all of the products!! I love how they do what they’re supposed to do and they don’t dry out my skin!! I’ve recently added the retinol cream and pimple patches and they work great!!
Lauren W. Verified Customer
Active Moisturizer and Retinol
My order came super fast and I’m so excited to use the active moisturizer and retinol system! I used it for the first time last night and it incorporated very nicely into my routine. Can’t wait to see the results
Fola Oluwatosin Verified Customer
This retinol is gentle but effective
This retinol is gentle but effective. My skin looks more even and refined, and I didn’t experience major irritation. It is a good option for gradual improvement and consistent use.

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